Identity & origin
BOTANICAL IDENTITY
The right name is the first step.
Kew describes this taxon as an annual. This notice concerns Phyllanthus amarus, family Phyllanthaceae. The pharmacopoeial material is: aerial parts.
Results are presented to explain the research; no self-medication recommendation.
Also known as: Phyllantus amarus Graines en bas feuilles, Phyllanthus amarus
Phyllanthus amarus must not be equated without checking with all products called Phyllanthus niruri. Identity and extract type are essential when interpreting a study.A photograph alone does not guarantee identification for consumption.
An illustration is not enough to identify a plant for consumption. Do not forage for a species based solely on this profile.
Uses & evidence
UNDERSTANDING THE USES
Properties & uses.
Mast cells: degranulation effect
Purified compounds were studied for release of allergy mediators. This is a cell finding, not a validated allergy treatment.
Laboratory or animal observation. A human benefit cannot be inferred from this finding alone.
Read the sourceThe traditional uses described are not clinical proof of effectiveness. Evidence for one preparation cannot automatically be applied to another.
Precautions before use
BEFORE ANY USE
Precautions & contraindications.
This guidance does not cover every individual situation. Missing information is not a guarantee of safety.
Contraindications & precautions
- Insufficient dataThis targeted audit does not provide a comprehensive contraindication review; this does not mean contraindications are absent.
Medicine interactions
- Insufficient dataThis dossier cannot establish compatibility with medication. A limited study does not replace an interaction review of the exact product.
Other retained warnings · review incomplete
These existing warnings remain relevant to consult. Their exhaustive reassessment is outside this targeted review.
Restrictions and precautions
- The references in this notice do not establish a complete contraindication list. This limitation does not mean absence of risk.
Medicine interactions
- Medicine compatibility is not assessed in this notice; a pharmacist should check it before any use.
Pregnancy, breastfeeding and children
The retained data do not support recommending medicinal use during pregnancy or breastfeeding.
No paediatric use is proposed; pharmacopoeial listing does not establish a child-appropriate dose.
“Reported” does not prove causality; “possible” may reflect indirect evidence. “None reported” means none in the cited source, not that all combinations have been studied. Do not stop a prescribed treatment based on this profile.
Adverse effects
- The inventory alone does not establish adverse-effect type or frequency.
Pregnancy & breastfeeding
The retained data do not support recommending medicinal use during pregnancy or breastfeeding.
Children & adolescents
No paediatric use is proposed; pharmacopoeial listing does not establish a child-appropriate dose.
If symptoms persist, worsen or are unusual, consult a healthcare professional. In an emergency, contact the emergency services.
Available evidence
EXPLORE THE EVIDENCE
The available evidence.
Purified compounds were studied for release of allergy mediators. This is a cell finding, not a validated allergy treatment.
Mast cells: degranulation effect
Isolated constituents reduced histamine and cytokines with modulation of Syk/PLCγ signalling.
Laboratory or animal observation. A human benefit cannot be inferred from this finding alone.
Read the referenceLimitations to keep in mind.
Do not replace allergy treatment or emergency care with this plant.
Studies, findings & limitations
THE RESEARCH
What the research shows.
A laboratory or animal result alone does not demonstrate a benefit in humans. Each result must be read alongside the preparation studied and its limitations.
Mast cells: degranulation effect
Laboratory or animal observation. A human benefit cannot be inferred from this finding alone.
- Type of research
- In-vitro study in activated mast cells.
- Preparation concerned
- Purified compounds from an ethyl-acetate fraction.
- Observed results
- Degranulation decreased under the experimental conditions.
- Limitations to consider
- Neither fraction nor concentrations correspond to tea. Human effectiveness and safety for this use remain to be established.
What can we take from this?
Neither fraction nor concentrations correspond to tea. Human effectiveness and safety for this use remain to be established.
Documentary review dated 09/10/2026. The references remain available to check the context.
Sources & last review
CHECKING REFERENCES
Sources for this profile.
- ANSM — French Pharmacopoeia, List A, January 2026, p. 27Accessed on 09/10/2026
- GBIF — taxonomy of Phyllanthus amarusAccessed on 09/10/2026
- Kew POWO — Phyllanthus amarus Schumach. & Thonn.Accessed on 09/10/2026
- Purified Compounds from Phyllanthus amarus Schum. & Thonn. Inhibit Mast Cell Degranulation via Modulation of Syk/PLCγ Signaling. — Vo TS et al. (2026)Accessed on 09/10/2026
Image: B. Phalan · CC BY 4.0. View the original image and its licence. Image resized and converted to WebP.